B152
Sigma
N6-Benzyl-5′-N-ethylcarboxamidoadenosine
solid
| Synonym: | N6-Benzyl-NECA |
| Linear Formula: | C19H22N6O4 |
| Molecular Weight: | 398.42 |
| MDL number: | MFCD00274027 |
Description
| Biochem/physiol Actions | Selective A3 adenosine receptor agonist. |
Properties
| form | solid |
| color | white |
| solubility | 45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 1.28 mg/mL |
| Gene Information | human ... ADORA3(140) |
| storage temp. | 2-8°C |
Safety
| WGK Germany | 3 |
References
| reference | Gallo-Rodriquez, et al., Structure-activity relationships of N6-benzyladenosine-5′-uronamides as selective adenosine agonists. J. Med. Chem. 37, 636, (1994) Abstract |
| Carruthers, et al., Adenosine A3 receptors: Two into one won’t go. Trends Pharmacol. Sci. 14, 290, (1993) Abstract | |
| Fozard, et al., Adenosine A3 receptors mediate hypotension in the angiotensin II-supported circulation of the pithed rat. Br. J. Pharmacol. 109, 3-5, (1993) Abstract |
